Links
- Mouse Genome Informatics (MGI) provides integrated web access to data on the genetics, genomics, and biology of the laboratory mouse.
- Mutant Mouse Regional Resource Centers (MMRRC) is a repository of mouse stocks and ES cell line collections for the genetics and biomedical research community.
- Ensembl Mouse provides annotation of the Mus musculus genome based on the NCBI m37 mouse assembly (April 2007, strain C57BL/6J). Ensembl provides gene builds for other eukaryotic genomes.
- Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders with references to published scientific articles, genetic sequence data and other sources.
- National Center for Biotechnology Information (NCBI) offers links to many databases including Structure (with 3-dimensional models of proteins), BLAST, Taxbrowser, OMIM, GEO and PubMed.
- FlyBase is a bioinformatics database of the biology and genome of the model organism Drosophila melanogaster and related insects.
- UniProt provides a comprehensive, high-quality and freely accessible resource of protein sequence and functional information, while the Human Protein Reference Database provides information specifically about the human proteome including protein expression, motifs and domains, function, and protein-protein interactions.
- Useful protein prediction tools include Simple Modular Architecture Research Tool (SMART), which produces schematic illustrations of protein motif structure; MUpro, which predicts protein stability changes caused by amino acid substitutions; MultiLoc, which predicts subcellular protein localization; ModBase, a database of 3D protein structures based on comparative modeling.
- SNPview at GNF is a database of single nucleotide polymorphisms (SNPs) and simple sequence length polymorphisms (SSLPs) that differ between common Mus musculus strains. It links to the expression anatomy database Symatlas, which presents data for transcript expression across many tissues in humans and mice.
- GenePaint is a digital atlas of gene expression patterns in the mouse, while The Allen Institute for Brain Science provides an excellent interactive, genome-wide image database of gene expression for the adult mouse brain, the developing mouse brain, the mouse spinal cord and the human cortex.
- RAPID (Resource of Asian Primary Immunodeficiency Diseases) is a web-based compendium of molecular alterations in primary immunodeficiency diseases.